hrp0092p3-216 | Pituitary, Neuroendocrinology and Puberty | ESPE2019

Family Central Early Puberty about Three Sisters

safi wajdi , Hadj Kacem Faten , Ben Mrad Fatma , El Arbi Kawthar , Gargouri Imene , Rekik nabila , Charfi Nadia , Mnif Feki Mouna , Abid Mohamed

Introduction: Early puberty is defined in the girl by the appearance of secondary sexual characteristics before the age of 8 years. Unlike the boy, the central origin is most often idiopathic. The familial nature encourages looking for a genetic mutation which can explain this early maturation of the gonadotropic axis.Cases: These are three girls from a consanguineous marriage. They had no particular pathological anteced...